Both independent researchers and research teams comprised of entities from the public sector, private sector, universities, or research centers may apply. Applicants must meet the following requirements: be a citizen of one of the 48 IDB member countries and not have immediate family members employed by the IDB Group (which includes the IDB, IDB Lab, and IDB Invest) or by CAF up to the fourth degree of consanguinity or second degree of affinity, including spouses.

Specialists from the IDB Group or CAF may participate in the projects by collaborating with the research teams; however, they must be formally associated with an external team and will not be eligible to receive financial compensation for their contributions. Funding will be transferred exclusively to external institutions or researchers leading the project and not to individuals affiliated with the IDB Group or CAF.